That means a lot of running and gunning, and I simply kept dying again and again. The resin is scattered all over the place but Lazaravic doesn't stand still much, and it takes A LOT of nearby resin explosions (even on easy mode) to make him go down. The only way to weaken Lazaravic, the final boss in Uncharted 2, is to shoot and explode a pile of blue resin while Lararavic is near it.